Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.K386Q

c.1156A>C

Surrounding Variants

1 paper

NM_000926.4

p.P383H

c.1148C>A

1 paper

NM_000926.4

p.P382Q

c.1145C>A

1 paper

NM_000926.4

p.E390K

c.1168G>A

1 paper

NM_000926.4

p.F380insFs

c.1140dupC

1 paper

NM_000926.4

p.F380S

c.1139T>C

1 paper

NM_000926.4

p.E392K

c.1174G>A

2 papers

NM_000926.4

p.D379insFs

c.1135_1136insA

1 paper

NM_000926.4

p.G393fs

c.1177_1178fs

2 papers

NM_000926.4

p.G393G

c.1179C>T

1 paper

NM_000926.4

p.A373T

c.1117G>A

1 paper

NM_000926.4

p.R399fs

c.1195_1196fs

1 paper

NM_000926.4

p.R399delFs

c.1196delC