Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000926.4

p.G334R

c.1000G>C

Surrounding Variants

3 papers

NM_000926.4

p.G334R

c.1000G>A

1 paper

NM_000926.4

p.G334V

c.1001G>T

1 paper

NM_000926.4

p.A335T

c.1003G>A

1 paper

NM_000926.4

p.A335V

c.1004C>T

2 papers

NM_000926.4

p.G332W

c.994G>T

1 paper

NM_000926.4

p.G331G

c.993C>T

1 paper

NM_000926.4

p.A336G

c.1007C>G

4 papers

NM_000926.4

p.G331A

c.992G>C

1 paper

NM_000926.4

p.G331S

c.991G>A

1 paper

NM_000926.4

p.S337ins1

c.1009_1010insGAA

2 papers

NM_000926.4

p.S337N

c.1010G>A

1 paper

NM_000926.4

p.D330E

c.990C>G