Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.L189P

c.566T>C

Surrounding Variants

1 paper

NM_000926.4

p.L189L

c.567G>A

1 paper

NM_000926.4

p.R187Q

c.560G>A

1 paper

NM_000926.4

p.R187W

c.559C>T

1 paper

NM_000926.4

p.P191fs

c.571_572fs

1 paper

NM_000926.4

p.A192P

c.574G>C

1 paper

NM_000926.4

p.A192T

c.574G>A

5 papers

NM_000926.4

p.P186L

c.557C>T

1 paper

NM_000926.4

p.A192V

c.575C>T

1 paper

NM_000926.4

p.P186S

c.556C>T

1 paper

NM_000926.4

p.K183R

c.548A>G

1 paper

NM_000926.4

p.S175_K183ins3

c.524_547dup24

1 paper

NM_000926.4

p.A180_H182del3

c.538_545del9