Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.S122L

c.365C>T

Surrounding Variants

2 papers

NM_000926.4

p.A120V

c.359C>T

1 paper

NM_000926.4

p.A120T

c.358G>A

1 paper

NM_000926.4

p.G125W

c.373G>T

2 papers

NM_000926.4

p.Q126*

c.376C>T

1 paper

NM_000926.4

p.L118P

c.353T>C

1 paper

NM_000926.4

p.Q126R

c.377A>G

1 paper

NM_000926.4

p.S127R

c.379A>C

1 paper

NM_000926.4

p.S127R

c.381C>G

2 papers

NM_000926.4

p.S127R

c.381C>A

1 paper

NM_000926.4

p.Q128E

c.382C>G

1 paper

NM_000926.4

p.P129S

c.385C>T

1 paper

NM_000926.4

p.L115insFs

c.344_345insC