Varaico: Literature-Extracted Genetic Variants

PGR

1,057 papers

RefSeq Summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated wit...

Pfam Domains

Prog_receptoraa 1–564UCSCProgesterone receptor

zf-C4aa 565–634UCSCDouble treble clef zinc finger, C4 type

Hormone_recepaa 704–891UCSCLigand-binding domain of nuclear hormone receptor

Gene Aliases

HGNC Name

progesterone receptor

HGNC Alias Symbols

PR; NR3C3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000926.4

p.D56E

c.168C>A

Surrounding Variants

1 paper

NM_000926.4

p.V48_D56del0

c.144_167del24

1 paper

NM_000926.4

p.L58I

c.172C>A

1 paper

NM_000926.4

p.S54F

c.161C>T

1 paper

NM_000926.4

p.F60Y

c.179T>A

1 paper

NM_000926.4

p.P61S

c.181C>T

1 paper

NM_000926.4

p.P61L

c.182C>T

1 paper

NM_000926.4

p.P61H

c.182C>A

1 paper

NM_000926.4

p.F60_P61del1

c.180_182delGGG

2 papers

NM_000926.4

p.I51T

c.152T>C

1 paper

NM_000926.4

p.R62insFs

c.185_186insA

1 paper

NM_000926.4

p.R62Q

c.185G>A

1 paper

NM_000926.4

p.A50A

c.150C>T