Varaico: Literature-Extracted Genetic Variants

PHC2

66 papers

RefSeq Summary

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimer...

Pfam Domains

zf-FCS_1aa 612–641UCSCZinc finger, FCS-type

PHC2_SAM_assocaa 642–761UCSCUnstructured region on Polyhomeotic-like protein 1 and 2

SAM_1aa 764–828UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

polyhomeotic homolog 2

HGNC Previous Symbol

EDR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001385109.1

p.D471N

c.1411G>A

Surrounding Variants

3 papers

NM_001385109.1

p.E475K

c.1423G>A

1 paper

NM_001385109.1

p.V476M

c.1426G>A

1 paper

NM_001385109.1

p.H519L

c.1556A>T

1 paper

NM_001385109.1

p.Q457*

c.1369C>T

1 paper

NM_001385109.1

p.V440M

c.1318G>A

1 paper

NM_001385109.1

p.E438K

c.1312G>A

1 paper

NM_001385109.1

p.P410S

c.1228C>T

1 paper

NM_001385109.1

p.A379T

c.1135G>A

3 papers

NM_001385109.1

p.R367Q

c.1100G>A

1 paper

NM_001385109.1

p.K342E

c.1024A>G