Varaico: Literature-Extracted Genetic Variants

PIDD1

87 papers

RefSeq Summary

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death...

Pfam Domains

LRR_8aa 125–183UCSCLeucine rich repeat

LRR_8aa 172–229UCSCLeucine rich repeat

LRR_8aa 194–252UCSCLeucine rich repeat

ZU5aa 324–417UCSCZU5 domain

Peptidase_S68aa 421–453UCSCPeptidase S68

ZU5aa 457–543UCSCZU5 domain

Gene Aliases

HGNC Name

p53-induced death domain protein 1

HGNC Previous Symbol

LRDD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145886.4

p.G800G

c.2400T>C

Surrounding Variants

4 papers

NM_145886.4

p.T788A

c.2362A>G

2 papers

NM_145886.4

p.R815W

c.2443C>T

1 paper

NM_145886.4

p.A782V

c.2345C>T

1 paper

NM_145886.4

p.R821Q

c.2462G>A

2 papers

NM_145886.4

p.A770delFs

c.2308delC

2 papers

NM_145886.4

p.A770fs

c.2308_2309fs

2 papers

NM_145886.4

p.R759G

c.2275A>G

2 papers

NM_145886.4

p.R759fs

c.2275_2276fs

2 papers

NM_145886.4

p.P758_R759Splc

c.2275-1G>A

2 papers

NM_145886.4

p.E737Q

c.2209G>C

1 paper

NM_145886.4

p.R825Q

c.2474G>A

1 paper

NM_145886.4

p.P729S

c.2185C>T