Varaico: Literature-Extracted Genetic Variants

PIDD1

87 papers

RefSeq Summary

The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death...

Pfam Domains

LRR_8aa 125–183UCSCLeucine rich repeat

LRR_8aa 172–229UCSCLeucine rich repeat

LRR_8aa 194–252UCSCLeucine rich repeat

ZU5aa 324–417UCSCZU5 domain

Peptidase_S68aa 421–453UCSCPeptidase S68

ZU5aa 457–543UCSCZU5 domain

Gene Aliases

HGNC Name

p53-induced death domain protein 1

HGNC Previous Symbol

LRDD

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_145886.4

p.N116H

c.346A>C

Surrounding Variants

1 paper

NM_145886.4

p.N116N

c.348C>T

1 paper

NM_145886.4

p.R102R

c.306C>G

1 paper

NM_145886.4

p.S136I

c.407G>T

1 paper

NM_145886.4

p.A152V

c.455C>T

1 paper

NM_145886.4

p.L170F

c.508C>T

1 paper

NM_145886.4

p.R182H

c.545G>A

1 paper

NM_145886.4

p.D200N

c.598G>A

1 paper

NM_145886.4

p.A237Splc

c.710-126T>C

1 paper

NM_145886.4

p.L59V

c.175C>G

1 paper

NM_145886.4

p.R261C

c.781C>T

1 paper

NM_145886.4

p.G45E

c.134G>A

1 paper

NM_145886.4

p.L270L

c.810G>A