Varaico: Literature-Extracted Genetic Variants

PIGR

128 papers

RefSeq Summary

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then trans...

Pfam Domains

V-setaa 23–128UCSCImmunoglobulin V-set domain

V-setaa 136–238UCSCImmunoglobulin V-set domain

V-setaa 241–341UCSCImmunoglobulin V-set domain

V-setaa 354–457UCSCImmunoglobulin V-set domain

V-setaa 465–562UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

polymeric immunoglobulin receptor

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002644.4

p.S684*

c.2051C>A

Surrounding Variants

1 paper

NM_002644.4

p.S684*

c.2051C>G

1 paper

NM_002644.4

p.E687K

c.2059G>A

1 paper

NM_002644.4

p.F692L

c.2074T>C

1 paper

NM_002644.4

p.F692L

c.2076T>G

1 paper

NM_002644.4

p.F692L

c.2076T>A

1 paper

NM_002644.4

p.A694G

c.2081C>G

1 paper

NM_002644.4

p.G699A

c.2096G>C

1 paper

NM_002644.4

p.S702P

c.2104T>C

1 paper

NM_002644.4

p.S702L

c.2105C>T

1 paper

NM_002644.4

p.E706insFs

c.2116dupG

1 paper

NM_002644.4

p.E706fs

c.2116_2117fs

1 paper

NM_002644.4

p.G710R

c.2128G>C