Varaico: Literature-Extracted Genetic Variants

PIGR

128 papers

RefSeq Summary

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then trans...

Pfam Domains

V-setaa 23–128UCSCImmunoglobulin V-set domain

V-setaa 136–238UCSCImmunoglobulin V-set domain

V-setaa 241–341UCSCImmunoglobulin V-set domain

V-setaa 354–457UCSCImmunoglobulin V-set domain

V-setaa 465–562UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

polymeric immunoglobulin receptor

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002644.4

p.V660Fs

c.1979delinsGTFs

Surrounding Variants

2 papers

NM_002644.4

p.V660A

c.1979T>C

1 paper

NM_002644.4

p.A661T

c.1981G>A

1 paper

NM_002644.4

p.R664W

c.1990C>T

1 paper

NM_002644.4

p.P646S

c.1936C>T

1 paper

NM_002644.4

p.A610V

c.1829C>T

1 paper

NM_002644.4

p.E607A

c.1820A>C

1 paper

NM_002644.4

p.E595Q

c.1783G>C

1 paper

NM_002644.4

p.P582R

c.1745C>G

13 papers

NM_002644.4

p.A580V

c.1739C>T

1 paper

NM_002644.4

p.S684*

c.2051C>G

1 paper

NM_002644.4

p.S684*

c.2051C>A

1 paper

NM_002644.4

p.E687K

c.2059G>A