Varaico: Literature-Extracted Genetic Variants

PIGR

128 papers

RefSeq Summary

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then trans...

Pfam Domains

V-setaa 23–128UCSCImmunoglobulin V-set domain

V-setaa 136–238UCSCImmunoglobulin V-set domain

V-setaa 241–341UCSCImmunoglobulin V-set domain

V-setaa 354–457UCSCImmunoglobulin V-set domain

V-setaa 465–562UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

polymeric immunoglobulin receptor

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002644.4

p.V518M

c.1552G>A

Surrounding Variants

1 paper

NM_002644.4

p.E522K

c.1564G>A

1 paper

NM_002644.4

p.R525Q

c.1574G>A

1 paper

NM_002644.4

p.Q509P

c.1526A>C

1 paper

NM_002644.4

p.L529fs

c.1585_1586fs

1 paper

NM_002644.4

p.N532I

c.1595A>T

1 paper

NM_002644.4

p.L533Q

c.1598T>A

1 paper

NM_002644.4

p.V534M

c.1600G>A

1 paper

NM_002644.4

p.T501M

c.1502C>T

1 paper

NM_002644.4

p.N500I

c.1499A>T

1 paper

NM_002644.4

p.W495*

c.1485G>A

1 paper

NM_002644.4

p.W495*

c.1484G>A

1 paper

NM_002644.4

p.S490L

c.1469C>T