Varaico: Literature-Extracted Genetic Variants

PIGR

128 papers

RefSeq Summary

This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then trans...

Pfam Domains

V-setaa 23–128UCSCImmunoglobulin V-set domain

V-setaa 136–238UCSCImmunoglobulin V-set domain

V-setaa 241–341UCSCImmunoglobulin V-set domain

V-setaa 354–457UCSCImmunoglobulin V-set domain

V-setaa 465–562UCSCImmunoglobulin V-set domain

Gene Aliases

HGNC Name

polymeric immunoglobulin receptor

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002644.4

p.A159G

c.476C>G

Surrounding Variants

3 papers

NM_002644.4

p.N158Y

c.472A>T

1 paper

NM_002644.4

p.R162del1

c.484_485delCCT

1 paper

NM_002644.4

p.Q168K

c.502C>A

1 paper

NM_002644.4

p.G170S

c.508G>A

1 paper

NM_002644.4

p.R146*

c.436A>T

1 paper

NM_002644.4

p.V176L

c.526G>C

1 paper

NM_002644.4

p.D136D

c.408C>T

1 paper

NM_002644.4

p.V183G

c.548T>G

1 paper

NM_002644.4

p.L133I

c.397C>A

1 paper

NM_002644.4

p.G189G

c.567A>T

1 paper

NM_002644.4

p.R192C

c.574C>T

1 paper

NM_002644.4

p.V206A

c.617T>C