Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001377334.1

p.E1595E

c.4785G>A

Surrounding Variants

1 paper

NM_001377334.1

p.E1595Q

c.4783G>C

1 paper

NM_001377334.1

p.V1592M

c.4774G>A

1 paper

NM_001377334.1

p.Q1584Q

c.4752G>A

6 papers

NM_001377334.1

p.R1610H

c.4829G>A

1 paper

NM_001377334.1

p.G1577W

c.4729G>T

1 paper

NM_001377334.1

p.W1623*

c.4868G>A

1 paper

NM_001377334.1

p.W1623*

c.4869G>A

1 paper

NM_001377334.1

p.F1624V

c.4870T>G

1 paper

NM_001377334.1

p.G1627R

c.4879G>C

1 paper

NM_001377334.1

p.G1627R

c.4879G>A

1 paper

NM_001377334.1

p.M1572I

c.4716G>T

1 paper

NM_001377334.1

p.M1572I

c.4716G>C