Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001377334.1

p.R1052G

c.3154A>G

Surrounding Variants

1 paper

NM_001377334.1

p.P1051S

c.3151C>T

1 paper

NM_001377334.1

p.G1048R

c.3142G>C

1 paper

NM_001377334.1

p.G1048R

c.3142G>A

1 paper

NM_001377334.1

p.K1047R

c.3140A>G

4 papers

NM_001377334.1

p.S1041T

c.3122G>C

1 paper

NM_001377334.1

p.S1041G

c.3121A>G

2 papers

NM_001377334.1

p.F1029L

c.3087C>G

2 papers

NM_001377334.1

p.F1029L

c.3087C>A

2 papers

NM_001377334.1

p.F1029L

c.3085T>C

1 paper

NM_001377334.1

p.R1020R

c.3060C>T

1 paper

NM_001377334.1

p.L1019I

c.3055C>A

1 paper

NM_001377334.1

p.Q1016_G1017Splc

c.3049-181G>A