Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001377334.1

p.K379M

c.1136A>T

Surrounding Variants

1 paper

NM_001377334.1

p.K379K

c.1137G>A

1 paper

NM_001377334.1

p.T381N

c.1142C>A

1 paper

NM_001377334.1

p.E375Q

c.1123G>C

1 paper

NM_001377334.1

p.D374delFs

c.1120delC

1 paper

NM_001377334.1

p.G373W

c.1117G>T

1 paper

NM_001377334.1

p.R386K

c.1157G>A

1 paper

NM_001377334.1

p.L387V

c.1159C>G

1 paper

NM_001377334.1

p.L387L

c.1161T>G

1 paper

NM_001377334.1

p.A390E

c.1169C>A

1 paper

NM_001377334.1

p.L391P

c.1172T>C

1 paper

NM_001377334.1

p.A364P

c.1090G>C

1 paper

NM_001377334.1

p.S363N

c.1088G>A