Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001377334.1

p.N321H

c.961A>C

Surrounding Variants

1 paper

NM_001377334.1

p.A320V

c.959C>T

1 paper

NM_001377334.1

p.P316L

c.947C>T

7 papers

NM_001377334.1

p.R315W

c.943C>T

2 papers

NM_001377334.1

p.E335G

c.1004A>G

1 paper

NM_001377334.1

p.A337V

c.1010C>T

1 paper

NM_001377334.1

p.I345Splc

c.1035-95G>T

1 paper

NM_001377334.1

p.R347*

c.1039C>T

1 paper

NM_001377334.1

p.R347G

c.1039C>G

2 papers

NM_001377334.1

p.R347Q

c.1040G>A

1 paper

NM_001377334.1

p.D351H

c.1051G>C

1 paper

NM_001377334.1

p.V361I

c.1081G>A

1 paper

NM_001377334.1

p.W362*

c.1085G>A