Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001377334.1

p.N232S

c.695A>G

Surrounding Variants

2 papers

NM_001377334.1

p.N232del1

c.694_696delATT

1 paper

NM_001377334.1

p.D229G

c.686A>G

1 paper

NM_001377334.1

p.D229Y

c.685G>T

1 paper

NM_001377334.1

p.Y228_I235del8

c.682_704del24

1 paper

NM_001377334.1

p.R237M

c.710G>T

1 paper

NM_001377334.1

p.D227V

c.680A>T

1 paper

NM_001377334.1

p.D227N

c.679G>A

1 paper

NM_001377334.1

p.S242L

c.725C>T

1 paper

NM_001377334.1

p.T243S

c.727A>T

1 paper

NM_001377334.1

p.T243S

c.728C>G

1 paper

NM_001377334.1

p.R221C

c.661C>T

1 paper

NM_001377334.1

p.Y244C

c.731A>G