Varaico: Literature-Extracted Genetic Variants

PIK3C2B

329 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 364–466UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 648–788UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 808–991UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 1077–1292UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1392–1477UCSCPX domain

C2aa 1517–1626UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta

HGNC Alias Symbols

C2-PI3K; PI3K-C2beta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001377334.1

p.S3delins

c.7delinsA

Surrounding Variants

2 papers

NM_001377334.1

p.S3L

c.8C>T

1 paper

NM_001377334.1

p.S3delins

c.7delinsT

1 paper

NM_001377334.1

p.M1delFs

c.1_2delAT

1 paper

NM_001377334.1

p.T4T

c.12T>C

1 paper

NM_001377334.1

p.M1L

c.1A>T

1 paper

NM_001377334.1

p.N7S

c.20A>G

1 paper

NM_001377334.1

p.N7T

c.20A>C

3 papers

NM_001377334.1

p.G8E

c.23G>A

1 paper

NM_001377334.1

p.V17_G18del2

c.49_53del6

2 papers

NM_001377334.1

p.R21H

c.62G>A

1 paper

NM_001377334.1

p.R21delFs

c.62delC

2 papers

NM_001377334.1

p.K22insFs

c.66dupA