Varaico: Literature-Extracted Genetic Variants

PIK3C2G

275 papers

RefSeq Summary

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell sur...

Pfam Domains

PI3K_rbdaa 274–371UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 542–650UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 686–870UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 956–1171UCSCPhosphatidylinositol 3- and 4-kinase

PXaa 1266–1348UCSCPX domain

C2aa 1382–1481UCSCC2 domain

Gene Aliases

HGNC Name

phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma

HGNC Previous Names

phosphoinositide-3-kinase, class 2, gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001288772.2

p.T276A

c.826A>G

Surrounding Variants

1 paper

NM_001288772.2

p.T274I

c.821C>T

1 paper

NM_001288772.2

p.S273R

c.819C>A

1 paper

NM_001288772.2

p.S273R

c.819C>G

1 paper

NM_001288772.2

p.S273R

c.817A>C

1 paper

NM_001288772.2

p.K270T

c.809A>C

1 paper

NM_001288772.2

p.L282F

c.844C>T

1 paper

NM_001288772.2

p.S268P

c.802T>C

1 paper

NM_001288772.2

p.K285N

c.855G>C

1 paper

NM_001288772.2

p.K285N

c.855G>T

1 paper

NM_001288772.2

p.F288I

c.862T>A

1 paper

NM_001288772.2

p.I290V

c.868A>G

5 papers

NM_001288772.2

p.A261E

c.782C>A