Varaico: Literature-Extracted Genetic Variants

PIK3CG

507 papers

RefSeq Summary

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I ca...

Pfam Domains

PIK3CG_ABDaa 1–192UCSCPIK3 catalytic subunit gamma adaptor-binding domain

PI3K_rbdaa 203–312UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 377–519UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 543–733UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 827–1044UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

HGNC Previous Names

phosphoinositide-3-kinase, catalytic, gamma polypeptide; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001282426.2

p.D238N

c.712G>A

Surrounding Variants

1 paper

NM_001282426.2

p.D238fs

c.712_713fs

1 paper

NM_001282426.2

p.P237fs

c.709_710fs

2 papers

NM_001282426.2

p.D239N

c.715G>A

1 paper

NM_001282426.2

p.P237delFs

c.709delC

1 paper

NM_001282426.2

p.P241delFs

c.723delC

1 paper

NM_001282426.2

p.S236fs

c.706_707fs

1 paper

NM_001282426.2

p.V235_S236insFs

c.705_706ins5

2 papers

NM_001282426.2

p.P241S

c.721C>T

1 paper

NM_001282426.2

p.P241H

c.722C>A

1 paper

NM_001282426.2

p.G242S

c.724G>A

1 paper

NM_001282426.2

p.G242fs

c.724_725fs

2 papers

NM_001282426.2

p.A243T

c.727G>A