Varaico: Literature-Extracted Genetic Variants

PIK3CG

507 papers

RefSeq Summary

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I ca...

Pfam Domains

PIK3CG_ABDaa 1–192UCSCPIK3 catalytic subunit gamma adaptor-binding domain

PI3K_rbdaa 203–312UCSCPI3-kinase family, ras-binding domain

PI3K_C2aa 377–519UCSCPhosphoinositide 3-kinase C2

PI3Kaaa 543–733UCSCPhosphoinositide 3-kinase family, accessory domain (PIK domain)

PI3_PI4_kinaseaa 827–1044UCSCPhosphatidylinositol 3- and 4-kinase

Gene Aliases

HGNC Name

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

HGNC Previous Names

phosphoinositide-3-kinase, catalytic, gamma polypeptide; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001282426.2

p.Q391H

c.1173A>T

Surrounding Variants

1 paper

NM_001282426.2

p.Q391H

c.1173A>C

1 paper

NM_001282426.2

p.G390E

c.1169G>A

1 paper

NM_001282426.2

p.V393I

c.1177G>A

2 papers

NM_001282426.2

p.G390V

c.1169G>T

1 paper

NM_001282426.2

p.H389Q

c.1167T>A

2 papers

NM_001282426.2

p.H389P

c.1166A>C

1 paper

NM_001282426.2

p.L394F

c.1180C>T

1 paper

NM_001282426.2

p.H389Y

c.1165C>T

1 paper

NM_001282426.2

p.Q396K

c.1186C>A

1 paper

NM_001282426.2

p.I387N

c.1160T>A

1 paper

NM_001282426.2

p.N386S

c.1157A>G

1 paper

NM_001282426.2

p.R398I

c.1193G>T