Varaico: Literature-Extracted Genetic Variants

PIK3R2

732 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions...

Pfam Domains

RhoGAPaa 125–259UCSCRhoGAP domain

SH2aa 330–405UCSCSH2 domain

PI3K_P85_iSH2aa 428–596UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 622–696UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 2

HGNC Alias Symbols

P85B; p85; p85beta; p85-BETA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005027.4

p.D29H

c.85G>C

Surrounding Variants

1 paper

NM_005027.4

p.D29N

c.85G>A

1 paper

NM_005027.4

p.V30M

c.88G>A

1 paper

NM_005027.4

p.L31M

c.91C>A

1 paper

NM_005027.4

p.V33G

c.98T>G

1 paper

NM_005027.4

p.E24A

c.71A>C

1 paper

NM_005027.4

p.E24G

c.71A>G

1 paper

NM_005027.4

p.V33V

c.99G>A

1 paper

NM_005027.4

p.E24Q

c.70G>C

1 paper

NM_005027.4

p.S34N

c.101G>A

1 paper

NM_005027.4

p.L23P

c.68T>C

2 papers

NM_005027.4

p.R35W

c.103C>T

2 papers

NM_005027.4

p.R35Q

c.104G>A