Varaico: Literature-Extracted Genetic Variants

PIK3R2

732 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions...

Pfam Domains

RhoGAPaa 125–259UCSCRhoGAP domain

SH2aa 330–405UCSCSH2 domain

PI3K_P85_iSH2aa 428–596UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 622–696UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 2

HGNC Alias Symbols

P85B; p85; p85beta; p85-BETA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005027.4

p.Q227*

c.679C>T

Surrounding Variants

2 papers

NM_005027.4

p.G230C

c.688G>T

1 paper

NM_005027.4

p.V232M

c.694G>A

12 papers

NM_005027.4

p.S234R

c.700A>C

11 papers

NM_005027.4

p.S234R

c.702C>A

11 papers

NM_005027.4

p.S234R

c.702C>G

1 paper

NM_005027.4

p.A219T

c.655G>A

1 paper

NM_005027.4

p.R218P

c.653G>C

1 paper

NM_005027.4

p.R218C

c.652C>T

1 paper

NM_005027.4

p.A236T

c.706G>A

1 paper

NM_005027.4

p.A236S

c.706G>T

1 paper

NM_005027.4

p.H217L

c.650A>T

1 paper

NM_005027.4

p.L214L

c.640C>T