Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

1–12 of 147 variants

15 papers

NM_003629.4

p.N283K

c.849T>A

14 papers

NM_003629.4

p.N283K

c.849T>G

5 papers

NM_003629.4

p.P41S

c.121C>T

5 papers

NM_003629.4

p.R325C

c.973C>T

3 papers

NM_003629.4

p.P127P

c.381T>A

3 papers

NM_003629.4

p.F226V

c.676T>G

3 papers

NM_003629.4

p.R309*

c.925C>T

2 papers

NM_003629.4

p.Y22C

c.65A>G

2 papers

NM_003629.4

p.K43T

c.128A>C

2 papers

NM_003629.4

p.R105W

c.313C>T

2 papers

NM_003629.4

p.H141H

c.423C>T

2 papers

NM_003629.4

p.Y202*

c.606T>A