Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.D347A

c.1040A>C

Surrounding Variants

1 paper

NM_003629.4

p.N344S

c.1031A>G

1 paper

NM_003629.4

p.D354G

c.1061A>G

1 paper

NM_003629.4

p.W358C

c.1074G>T

1 paper

NM_003629.4

p.W358C

c.1074G>C

1 paper

NM_003629.4

p.E361E

c.1083G>A

2 papers

NM_003629.4

p.R365*

c.1093C>T

1 paper

NM_003629.4

p.K375_P376ins5

c.1123_1127ins15

1 paper

NM_003629.4

p.F380S

c.1139T>C

1 paper

NM_003629.4

p.F380L

c.1140C>G

1 paper

NM_003629.4

p.R383C

c.1147C>T

1 paper

NM_003629.4

p.R383L

c.1148G>T

1 paper

NM_003629.4

p.G389*

c.1165G>T