Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.N334K

c.1002T>G

Surrounding Variants

1 paper

NM_003629.4

p.N334K

c.1002T>A

1 paper

NM_003629.4

p.E335A

c.1004A>C

1 paper

NM_003629.4

p.D338A

c.1013A>C

1 paper

NM_003629.4

p.W329*

c.987G>A

1 paper

NM_003629.4

p.W329*

c.986G>A

1 paper

NM_003629.4

p.V328I

c.982G>A

1 paper

NM_003629.4

p.L326R

c.977T>G

5 papers

NM_003629.4

p.R325C

c.973C>T

2 papers

NM_003629.4

p.N317S

c.950A>G

1 paper

NM_003629.4

p.W315S

c.944G>C

1 paper

NM_003629.4

p.N344S

c.1031A>G

1 paper

NM_003629.4

p.D347A

c.1040A>C