Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003629.4

p.P300P

c.900T>A

Surrounding Variants

1 paper

NM_003629.4

p.L302P

c.905T>C

2 papers

NM_003629.4

p.S297S

c.891C>T

1 paper

NM_003629.4

p.M295fs

c.883_884fs

1 paper

NM_003629.4

p.M295delFs

c.883delT

1 paper

NM_003629.4

p.R306*

c.916C>T

1 paper

NM_003629.4

p.R306Q

c.917G>A

2 papers

NM_003629.4

p.M295fs

c.883_884fs

1 paper

NM_003629.4

p.Q304_L305del2

c.910_914del6

1 paper

NM_003629.4

p.K307N

c.921G>T

1 paper

NM_003629.4

p.K307N

c.921G>C

3 papers

NM_003629.4

p.R309*

c.925C>T

1 paper

NM_003629.4

p.R309G

c.925C>G