Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.S273S

c.819C>T

Surrounding Variants

1 paper

NM_003629.4

p.G268A

c.803G>C

1 paper

NM_003629.4

p.D280N

c.838G>A

1 paper

NM_003629.4

p.R266C

c.796C>T

1 paper

NM_003629.4

p.K264R

c.791A>G

1 paper

NM_003629.4

p.K264E

c.790A>G

14 papers

NM_003629.4

p.N283K

c.849T>G

15 papers

NM_003629.4

p.N283K

c.849T>A

1 paper

NM_003629.4

p.Q284H

c.852A>T

1 paper

NM_003629.4

p.Q284H

c.852A>C

1 paper

NM_003629.4

p.D292N

c.874G>A

2 papers

NM_003629.4

p.M295fs

c.883_884fs

1 paper

NM_003629.4

p.M295delFs

c.883delT