Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.Q229R

c.686A>G

Surrounding Variants

3 papers

NM_003629.4

p.F226V

c.676T>G

1 paper

NM_003629.4

p.T222I

c.665C>T

1 paper

NM_003629.4

p.Y240C

c.719A>G

1 paper

NM_003629.4

p.E217G

c.650A>G

1 paper

NM_003629.4

p.E242*

c.724G>T

1 paper

NM_003629.4

p.T214delFs

c.640delT

1 paper

NM_003629.4

p.R213S

c.639G>T

1 paper

NM_003629.4

p.R213S

c.639G>C

1 paper

NM_003629.4

p.R246*

c.736A>T

1 paper

NM_003629.4

p.G248E

c.743G>A

1 paper

NM_003629.4

p.Q207_E208Splc

c.621+2T>G

2 papers

NM_003629.4

p.Y202*

c.606T>A