Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.L156P

c.467T>C

Surrounding Variants

1 paper

NM_003629.4

p.V154M

c.460G>A

1 paper

NM_003629.4

p.P159T

c.475C>A

1 paper

NM_003629.4

p.V160V

c.480G>C

1 paper

NM_003629.4

p.S161A

c.481T>G

1 paper

NM_003629.4

p.P150S

c.448C>T

2 papers

NM_003629.4

p.H141H

c.423C>T

1 paper

NM_003629.4

p.H141N

c.421C>A

1 paper

NM_003629.4

p.E135Q

c.403G>C

1 paper

NM_003629.4

p.V133A

c.398T>C

1 paper

NM_003629.4

p.S132S

c.396C>T

1 paper

NM_003629.4

p.S132F

c.395C>T

3 papers

NM_003629.4

p.P127P

c.381T>A