Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.Q61*

c.181C>T

Surrounding Variants

1 paper

NM_003629.4

p.Q61E

c.181C>G

1 paper

NM_003629.4

p.Q61R

c.182A>G

1 paper

NM_003629.4

p.A63T

c.187G>A

1 paper

NM_003629.4

p.S57F

c.170C>T

1 paper

NM_003629.4

p.W65L

c.194G>T

1 paper

NM_003629.4

p.G68E

c.203G>A

1 paper

NM_003629.4

p.I70N

c.209T>A

1 paper

NM_003629.4

p.A48E

c.143C>A

1 paper

NM_003629.4

p.S47*

c.140C>G

1 paper

NM_003629.4

p.S47T

c.139T>A

1 paper

NM_003629.4

p.K43M

c.128A>T

1 paper

NM_003629.4

p.K43R

c.128A>G