Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.P41L

c.122C>T

Surrounding Variants

1 paper

NM_003629.4

p.P41delins

c.121_122delinsTT

5 papers

NM_003629.4

p.P41S

c.121C>T

1 paper

NM_003629.4

p.K43M

c.128A>T

1 paper

NM_003629.4

p.K43R

c.128A>G

2 papers

NM_003629.4

p.K43T

c.128A>C

1 paper

NM_003629.4

p.P38A

c.112C>G

1 paper

NM_003629.4

p.L37H

c.110T>A

1 paper

NM_003629.4

p.A36A

c.108T>A

1 paper

NM_003629.4

p.S47T

c.139T>A

1 paper

NM_003629.4

p.A36Splc

c.107-3T>C

1 paper

NM_003629.4

p.S47*

c.140C>G

1 paper

NM_003629.4

p.A48E

c.143C>A