Varaico: Literature-Extracted Genetic Variants

PIK3R3

298 papers

RefSeq Summary

Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and ...

Pfam Domains

SH2aa 65–140UCSCSH2 domain

PI3K_P85_iSH2aa 163–331UCSCPhosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain

SH2aa 358–432UCSCSH2 domain

Gene Aliases

HGNC Name

phosphoinositide-3-kinase regulatory subunit 3

HGNC Alias Symbol

p55

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003629.4

p.Y29H

c.85T>C

Surrounding Variants

1 paper

NM_003629.4

p.I27delFs

c.79_80delAT

1 paper

NM_003629.4

p.I27V

c.79A>G

1 paper

NM_003629.4

p.E25K

c.73G>A

2 papers

NM_003629.4

p.Y22C

c.65A>G

1 paper

NM_003629.4

p.P21H

c.62C>A

1 paper

NM_003629.4

p.D12E

c.36C>G

1 paper

NM_003629.4

p.D12E

c.36C>A

1 paper

NM_003629.4

p.D11N

c.31G>A

1 paper

NM_003629.4

p.D9N

c.25G>A

1 paper

NM_003629.4

p.M1I

c.3G>T