Varaico: Literature-Extracted Genetic Variants

Gene:PIM1
Variant:p.E121K

PIM1

235 papers

RefSeq Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematop...

Pfam Domains

Pkinaseaa 38–290UCSCProtein kinase domain
Pkinaseaa 38–290UCSCProtein kinase domain

Gene Aliases

HGNC Name

Pim-1 proto-oncogene, serine/threonine kinase

HGNC Previous Name

pim-1 oncogene

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
5 papers
NM_002648.4
p.E121K
c.361G>A
Surrounding Variants
1 paper
NM_002648.4
p.E121Q
c.361G>C
3 papers
NM_002648.4
p.E121*
c.361G>T
1 paper
NM_002648.4
p.E121G
c.362A>G
1 paper
NM_002648.4
p.L120L
c.360G>A
3 papers
NM_002648.4
p.L120L
c.360G>T
1 paper
NM_002648.4
p.L120_E121delins
c.360_361delinsAC
1 paper
NM_002648.4
p.R122_E124del3
c.364_371del9
1 paper
NM_002648.4
p.R122_E124del0
c.365_370del6
1 paper
NM_002648.4
p.I119M
c.357C>G
1 paper
NM_002648.4
p.R122S
c.366G>T
1 paper
NM_002648.4
p.I119_L120delFs
c.356_360del5
1 paper
NM_002648.4
p.P123S
c.367C>T
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