Varaico: Literature-Extracted Genetic Variants

Gene:PIM1
Variant:p.E124K

PIM1

235 papers

RefSeq Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematop...

Pfam Domains

Pkinaseaa 38–290UCSCProtein kinase domain
Pkinaseaa 38–290UCSCProtein kinase domain

Gene Aliases

HGNC Name

Pim-1 proto-oncogene, serine/threonine kinase

HGNC Previous Name

pim-1 oncogene

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002648.4
p.E124K
c.370G>A
Surrounding Variants
10 papers
NM_002648.4
p.E124Q
c.370G>C
1 paper
NM_002648.4
p.E124*
c.370G>T
1 paper
NM_002648.4
p.P123R
c.368C>G
1 paper
NM_002648.4
p.E124D
c.372G>C
1 paper
NM_002648.4
p.E124D
c.372G>T
2 papers
NM_002648.4
p.P125T
c.373C>A
2 papers
NM_002648.4
p.P125A
c.373C>G
11 papers
NM_002648.4
p.P125S
c.373C>T
1 paper
NM_002648.4
p.P123S
c.367C>T
1 paper
NM_002648.4
p.R122S
c.366G>T
1 paper
NM_002648.4
p.R122_E124del0
c.365_370del6
4 papers
NM_002648.4
p.V126M
c.376G>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."