Varaico: Literature-Extracted Genetic Variants

Gene:PIM1
Variant:p.E135K

PIM1

235 papers

RefSeq Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematop...

Pfam Domains

Pkinaseaa 38–290UCSCProtein kinase domain
Pkinaseaa 38–290UCSCProtein kinase domain

Gene Aliases

HGNC Name

Pim-1 proto-oncogene, serine/threonine kinase

HGNC Previous Name

pim-1 oncogene

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
23 papers
NM_002648.4
p.E135K
c.403G>A
NM_001243186.2
p.E226K
c.676G>A
Surrounding Variants
4 papers
NM_002648.4
p.E135Q
c.403G>C
6 papers
NM_002648.4
p.E135*
c.403G>T
1 paper
NM_002648.4
p.E135Fs
c.403delinsTAFs
1 paper
NM_002648.4
p.E135G
c.404A>G
1 paper
NM_002648.4
p.E135_A138delFs
c.405_414del10
1 paper
NM_002648.4
p.E135insFs
c.403dupG
1 paper
NM_002648.4
p.T134R
c.401C>G
1 paper
NM_002648.4
p.T134M
c.401C>T
1 paper
NM_002648.4
p.E135_G137delFs
c.405_411del7
1 paper
NM_002648.4
p.G137delFs
c.409delG
1 paper
NM_002648.4
p.R136fs
c.406_407fs
1 paper
NM_002648.4
p.I133I
c.399C>A
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