Varaico: Literature-Extracted Genetic Variants

Gene:PIM1
Variant:p.E142D

PIM1

235 papers

RefSeq Summary

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematop...

Pfam Domains

Pkinaseaa 38–290UCSCProtein kinase domain
Pkinaseaa 38–290UCSCProtein kinase domain

Gene Aliases

HGNC Name

Pim-1 proto-oncogene, serine/threonine kinase

HGNC Previous Name

pim-1 oncogene

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_002648.4
p.E142D
c.426G>T
Surrounding Variants
6 papers
NM_002648.4
p.E142D
c.426G>C
1 paper
NM_002648.4
p.E142G
c.425A>G
2 papers
NM_002648.4
p.L143V
c.427C>G
1 paper
NM_002648.4
p.L143L
c.427C>T
1 paper
NM_002648.4
p.E142K
c.424G>A
1 paper
NM_002648.4
p.E142Q
c.424G>C
1 paper
NM_002648.4
p.E142*
c.424G>T
1 paper
NM_002648.4
p.E142_L143delins
c.424_427delinsCAGG
1 paper
NM_002648.4
p.L143R
c.428T>G
1 paper
NM_002648.4
p.A144P
c.430G>C
4 papers
NM_002648.4
p.E141K
c.421G>A
1 paper
NM_002648.4
p.E141Q
c.421G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."