Varaico: Literature-Extracted Genetic Variants

Gene:PIM2
Variant:p.Y194N

PIM2

43 papers

RefSeq Summary

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival.[provided by RefSeq...

Pfam Domains

Pkinaseaa 32–286UCSCProtein kinase domain

Gene Aliases

HGNC Name

Pim-2 proto-oncogene, serine/threonine kinase

HGNC Previous Name

pim-2 oncogene

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_006875.4
p.Y194N
c.580T>A
Surrounding Variants
1 paper
NM_006875.4
p.H190Y
c.568C>T
1 paper
NM_006875.4
p.G184D
c.551G>A
1 paper
NM_006875.4
p.R174C
c.520C>T
1 paper
NM_006875.4
p.I164V
c.490A>G
1 paper
NM_006875.4
p.R162C
c.484C>T
1 paper
NM_006875.4
p.G158E
c.473G>A
1 paper
NM_006875.4
p.C154Y
c.461G>A
1 paper
NM_006875.4
p.R141H
c.422G>A
1 paper
NM_006875.4
p.R141C
c.421C>T
1 paper
NM_006875.4
p.D127H
c.379G>C
1 paper
NM_006875.4
p.F106S
c.317T>C
1 paper
NM_006875.4
p.G98V
c.293G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."