Varaico: Literature-Extracted Genetic Variants

Gene:PKM
Variant:p.F12Y

PKM

313 papers

RefSeq Summary

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruv...

Pfam Domains

PKaa 116–449UCSCPyruvate kinase, barrel domain
PK_Caa 484–602UCSCPyruvate kinase, alpha/beta domain

Gene Aliases

HGNC Name

pyruvate kinase M1/2

HGNC Previous Symbol

PKM2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002654.6
p.F12Y
c.35T>A
Surrounding Variants
1 paper
NM_002654.6
p.F12L
c.36C>A
1 paper
NM_002654.6
p.I13I
c.39T>A
1 paper
NM_002654.6
p.Q14E
c.40C>G
1 paper
NM_002654.6
p.A8V
c.23C>T
1 paper
NM_002654.6
p.Q16R
c.47A>G
1 paper
NM_002654.6
p.Q16H
c.48G>T
1 paper
NM_002654.6
p.Q16H
c.48G>C
1 paper
NM_002654.6
p.L18Q
c.53T>A
1 paper
NM_002654.6
p.H5R
c.14A>G
1 paper
NM_002654.6
p.K3T
c.8A>C
1 paper
NM_002654.6
p.M1del1
c.1_2delCAT
1 paper
NM_002654.6
p.M1I
c.3G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."