Varaico: Literature-Extracted Genetic Variants

PKN1

137 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinas...

Pfam Domains

HR1aa 38–102UCSCHr1 repeat

HR1aa 127–196UCSCHr1 repeat

HR1aa 214–281UCSCHr1 repeat

Pkinaseaa 615–874UCSCProtein kinase domain

Pkinase_Caa 895–937UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase N1

HGNC Previous Symbol

PRKCL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002741.5

p.D65A

c.194A>C

Surrounding Variants

1 paper

NM_002741.5

p.R68S

c.202C>A

1 paper

NM_002741.5

p.R68G

c.202C>G

1 paper

NM_002741.5

p.R68C

c.202C>T

1 paper

NM_002741.5

p.L59M

c.175C>A

1 paper

NM_002741.5

p.R78Q

c.233G>A

1 paper

NM_002741.5

p.E49K

c.145G>A

1 paper

NM_002741.5

p.R83H

c.248G>A

1 paper

NM_002741.5

p.L84H

c.251T>A

1 paper

NM_002741.5

p.L87Q

c.260T>A

1 paper

NM_002741.5

p.E40K

c.118G>A

1 paper

NM_002741.5

p.P29P

c.87C>A

1 paper

NM_002741.5

p.A105T

c.313G>A