Varaico: Literature-Extracted Genetic Variants

PKN1

137 papers

RefSeq Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinas...

Pfam Domains

HR1aa 38–102UCSCHr1 repeat

HR1aa 127–196UCSCHr1 repeat

HR1aa 214–281UCSCHr1 repeat

Pkinaseaa 615–874UCSCProtein kinase domain

Pkinase_Caa 895–937UCSCProtein kinase C terminal domain

Gene Aliases

HGNC Name

protein kinase N1

HGNC Previous Symbol

PRKCL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002741.5

p.L924L

c.2772C>T

Surrounding Variants

2 papers

NM_002741.5

p.A921V

c.2762C>T

2 papers

NM_002741.5

p.P917L

c.2750C>T

1 paper

NM_002741.5

p.F935F

c.2805C>T

1 paper

NM_002741.5

p.G941G

c.2823C>T

1 paper

NM_002741.5

p.E907K

c.2719G>A

1 paper

NM_002741.5

p.V901I

c.2701G>A

1 paper

NM_002741.5

p.E866D

c.2598A>C

1 paper

NM_002741.5

p.E866D

c.2598A>T

1 paper

NM_002741.5

p.L858R

c.2573T>G

1 paper

NM_002741.5

p.M846insFs

c.2537_2538insC

1 paper

NM_002741.5

p.A840ins3

c.2519_2520ins9

1 paper

NM_002741.5

p.T790M

c.2369C>T