PBX/knotted 1 homeobox 2

Homeobox protein PKNOX2

Homeobox protein PREP-2

PBX/knotted homeobox 2

TALE/MEIS homeobox family N-terminal domain

Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009].

Varaico: Literature-Extracted Genetic Variants

PKNOX2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name