Varaico: Literature-Extracted Genetic Variants

Gene:PLA2G3
Variant:p.R365C

PLA2G3

48 papers

RefSeq Summary

This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium...

Pfam Domains

Phospholip_A2_2aa 152–248UCSCPhospholipase A2
Phospholip_A2_2aa 356–429UCSCPhospholipase A2

Gene Aliases

HGNC Name

phospholipase A2 group III

HGNC Alias Symbol

GIII-SPLA2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_015715.5
p.R365C
c.1093C>T
Surrounding Variants
2 papers
NM_015715.5
p.R362C
c.1084C>T
1 paper
NM_015715.5
p.R378W
c.1132C>T
1 paper
NM_015715.5
p.P411R
c.1232C>G
1 paper
NM_015715.5
p.K323E
c.967A>G
3 papers
NM_015715.5
p.S322R
c.966C>G
3 papers
NM_015715.5
p.S322R
c.966C>A
3 papers
NM_015715.5
p.S322R
c.964A>C
1 paper
NM_015715.5
p.R309Q
c.926G>A
1 paper
NM_015715.5
p.R303Q
c.908G>A
1 paper
NM_015715.5
p.R303*
c.907C>T
1 paper
NM_015715.5
p.A298D
c.893C>A
1 paper
NM_015715.5
p.S296R
c.888C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."