Varaico: Literature-Extracted Genetic Variants

PLA2G4D

62 papers

RefSeq Summary

The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004...

Pfam Domains

C2aa 22–126UCSCC2 domain

cPLA2_C2aa 163–270UCSCCytosolic phospholipases A2 C2-domain

PLA2_Baa 323–562UCSCLysophospholipase catalytic domain

Gene Aliases

HGNC Name

phospholipase A2 group IVD

HGNC Alias Symbol

cPLA2delta

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_178034.4

p.S434T

c.1300T>A

Surrounding Variants

1 paper

NM_178034.4

p.Y408S

c.1223A>C

1 paper

NM_178034.4

p.T336I

c.1007C>T

1 paper

NM_178034.4

p.P275R

c.824C>G

1 paper

NM_178034.4

p.E272K

c.814G>A

1 paper

NM_178034.4

p.A262V

c.785C>T

1 paper

NM_178034.4

p.P258S

c.772C>T

2 papers

NM_178034.4

p.G238R

c.712G>C

2 papers

NM_178034.4

p.G238R

c.712G>A

1 paper

NM_178034.4

p.N232D

c.694A>G

1 paper

NM_178034.4

p.A213V

c.638C>T

1 paper

NM_178034.4

p.D179Splc

c.535+2T>C

1 paper

NM_178034.4

p.D179Splc

c.535+1G>A