Varaico: Literature-Extracted Genetic Variants

PLAGL1

55 papers

RefSeq Summary

This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this g...

Pfam Domains

zf-C2H2aa 32–56UCSCZinc finger, C2H2 type

zf-C2H2aa 62–84UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

PLAG1 like zinc finger 1

HGNC Alias Symbols

ZAC; LOT1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001317162.2

p.P297A

c.889C>G

Surrounding Variants

1 paper

NM_001317162.2

p.N300I

c.899A>T

1 paper

NM_001317162.2

p.S290S

c.870C>T

1 paper

NM_001317162.2

p.N304T

c.911A>C

1 paper

NM_001317162.2

p.T308A

c.922A>G

1 paper

NM_001317162.2

p.S309A

c.925T>G

1 paper

NM_001317162.2

p.A271_Q276delFs

c.813_826del14

1 paper

NM_001317162.2

p.L318H

c.953T>A

1 paper

NM_001317162.2

p.K323fs

c.967_968fs

1 paper

NM_001317162.2

p.K323_I328delFs

c.969_982del14

1 paper

NM_001317162.2

p.D333N

c.997G>A

1 paper

NM_001317162.2

p.P342delFs

c.1024delG

1 paper

NM_001317162.2

p.T227A

c.679A>G