Varaico: Literature-Extracted Genetic Variants

Gene:PLAU
Variant:p.V15L

PLAU

227 papers

RefSeq Summary

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate...

Pfam Domains

Kringleaa 70–151UCSCKringle domain
Kringleaa 70–151UCSCKringle domain
Trypsinaa 162–402UCSCTrypsin

Gene Aliases

HGNC Name

plasminogen activator, urokinase

HGNC Alias Symbols

URK; UPA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
7 papers
NM_002658.6
p.V15L
c.43G>C
Surrounding Variants
7 papers
NM_002658.6
p.V15L
c.43G>T
1 paper
NM_002658.6
p.S18S
c.54C>T
1 paper
NM_002658.6
p.K19E
c.55A>G
1 paper
NM_002658.6
p.L10I
c.28C>A
1 paper
NM_002658.6
p.L9L
c.27T>C
1 paper
NM_002658.6
p.L9H
c.26T>A
1 paper
NM_002658.6
p.L9F
c.25C>T
1 paper
NM_002658.6
p.L5V
c.13C>G
1 paper
NM_002658.6
p.L4L
c.10C>T
1 paper
NM_002658.6
p.A3V
c.8C>T
1 paper
NM_002658.6
p.M1T
c.2T>C
1 paper
NM_002658.6
p.M1V
c.1A>G
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