Varaico: Literature-Extracted Genetic Variants

Gene:PLAU
Variant:p.P93P

PLAU

227 papers

RefSeq Summary

This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate...

Pfam Domains

Kringleaa 70–151UCSCKringle domain
Kringleaa 70–151UCSCKringle domain
Trypsinaa 162–402UCSCTrypsin

Gene Aliases

HGNC Name

plasminogen activator, urokinase

HGNC Alias Symbols

URK; UPA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002658.6
p.P93P
c.279C>A
Surrounding Variants
1 paper
NM_002658.6
p.C91Y
c.272G>A
1 paper
NM_002658.6
p.P90delFs
c.270delC
1 paper
NM_002658.6
p.T98A
c.292A>G
1 paper
NM_002658.6
p.R89L
c.266G>T
1 paper
NM_002658.6
p.M87T
c.260T>C
4 papers
NM_002658.6
p.T86A
c.256A>G
1 paper
NM_002658.6
p.D85E
c.255C>A
2 papers
NM_002658.6
p.G80R
c.238G>A
1 paper
NM_002658.6
p.H107H
c.321C>T
1 paper
NM_002658.6
p.R108insFs
c.323_324ins10
1 paper
NM_002658.6
p.H76H
c.228C>T
1 paper
NM_002658.6
p.G75D
c.224G>A
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."