Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.D392E

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006622.4
p.D392E
c.1176T>G
Surrounding Variants
1 paper
NM_006622.4
p.D392E
c.1176T>A
1 paper
NM_006622.4
p.E391*
c.1171G>T
1 paper
NM_006622.4
p.D394_I395insFs
c.1182_1183insT
1 paper
NM_006622.4
p.K390N
c.1170A>T
1 paper
NM_006622.4
p.K390N
c.1170A>C
1 paper
NM_006622.4
p.S389A
c.1165T>G
3 papers
NM_006622.4
p.R387_V388delFs
c.1161_1162delCT
3 papers
NM_006622.4
p.R387fs
c.1159_1160fs
2 papers
NM_006622.4
p.K404N
c.1212G>T
2 papers
NM_006622.4
p.K404N
c.1212G>C
1 paper
NM_006622.4
p.Q409*
c.1225C>T
2 papers
NM_006622.4
p.D417H
c.1249G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."