Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.R342S

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006622.4
p.R342S
c.1026A>C
Surrounding Variants
1 paper
NM_006622.4
p.R342S
c.1026A>T
1 paper
NM_006622.4
p.G337D
c.1010G>A
1 paper
NM_006622.4
p.D353Y
c.1057G>T
1 paper
NM_006622.4
p.D353H
c.1057G>C
1 paper
NM_006622.4
p.S357*
c.1070C>G
1 paper
NM_006622.4
p.S357*
c.1070C>A
1 paper
NM_006622.4
p.K361*
c.1081A>T
1 paper
NM_006622.4
p.K361R
c.1082A>G
2 papers
NM_006622.4
p.F363L
c.1087T>C
2 papers
NM_006622.4
p.F363L
c.1089C>G
2 papers
NM_006622.4
p.F363L
c.1089C>A
1 paper
NM_006622.4
p.L335delFs
c.1005delC
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."