Varaico: Literature-Extracted Genetic Variants

Gene:PLK2
Variant:p.L335delFs

PLK2

162 papers

RefSeq Summary

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen a...

Pfam Domains

Pkinaseaa 68–320UCSCProtein kinase domain
POLO_boxaa 498–555UCSCPOLO box duplicated region
POLO_boxaa 594–659UCSCPOLO box duplicated region

Gene Aliases

HGNC Name

polo like kinase 2

HGNC Alias Symbol

SNK

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
4 papers
NM_006622.4
p.L335delFs
c.1004delA
Surrounding Variants
1 paper
NM_006622.4
p.L335insFs
c.1004dupT
4 papers
NM_006622.4
p.L335fs
c.1003_1004fs
1 paper
NM_006622.4
p.L335delFs
c.1005delC
3 papers
NM_006622.4
p.L335fs
c.1003_1004fs
1 paper
NM_006622.4
p.D327N
c.979G>A
1 paper
NM_006622.4
p.D326G
c.977A>G
1 paper
NM_006622.4
p.P306S
c.916C>T
1 paper
NM_006622.4
p.G337D
c.1010G>A
1 paper
NM_006622.4
p.P300P
c.900G>A
1 paper
NM_006622.4
p.P300L
c.899C>T
1 paper
NM_006622.4
p.R342S
c.1026A>T
1 paper
NM_006622.4
p.R342S
c.1026A>C
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